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About James Weiss, MD

My name is James Weiss, MD but I’ve always been called Jed. I moved to Chapel Hill from the San Francisco Bay Area 2 years ago after spending 10 years on the Clinical Faculty at Stanford University’s Medical Center as the psychiatric consultant to the Stanford inpatient pain program. I have been practicing psychiatry for many years and during that time, I’ve been in private practice, been Medical Director of two hospitals and have been on the clinical faculty and staff at UCLA, UCSF and Stanford. I have often been involved in teaching interns, residents and fellows at these hospitals and have really enjoyed it. Over the past 10 or 12 years, I’ve had a special interest in the psychiatric aspects of pain medicine, but I’ve also spent many years as a general psychiatrist and psychotherapist with interests in post-traumatic stress disorders, including sexual, environmental and occupational traumas, anxiety, depression and couples issues. I was trained at the UCLA Neuropsychiatric Institute after going to Medical School at USC in Los Angeles. With a long-standing interest in psychotherapy, my philosophy as a psychiatrist is always to think about what is best for my patients and to encourage them to develop coping skills to deal with the challenges they face. This can include good medication practices as well as reflective therapeutic approaches. At Stanford as well as other places, I’ve had the opportunity to collaborate with some truly exceptional psychologists and physicians, which has served me well. Based on feedback I have received, my patients have consistently found me to be thoughtful and approachable. 

Partial List of Treatment Areas

  • Adjustment Concerns
  • Anxiety / Stress
  • Cognitive Disorder
  • Depression
  • Developmental Disability / Autism
  • Compulsive Gambling
  • Hoarding
  • OCD
  • Personality Disorder
  • Post-Partum / Pregnancy Depression
  • PTSD/Trauma
  • Sex / Pornography Addiction
  • Pain Disorder
  • badge-3 TelehealthSignifies the completion of a mental health telehealth training program

Education & Certifications

– Doctor of Medicine from the University of Southern California s School of Medicine in Los Angeles, CA
– Bachelor of Art from Northwestern University in Evanston, IL
– Board Certified by the American Board of Psychiatry and Neurology

Accepted Insurance

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July 27, 2021



July 16, 2021

Dr. Wiess has helped me a lot


July 13, 2021

Dr. Weiss is excellent! He s so caring and genuine which makes for a comfortable patient and provider atmosphere. Highly recommend him!


June 25, 2021

I like my doctor and he has prescribed meds that help with my depression & anxiety. I've begun talking about my core issues which are hard for me, he understands me.


June 17, 2021

It works really well for me and James is a great listener and pragmatic partner


June 8, 2021

The app is awesome. Very easy to use.


May 26, 2021

Dr. Weiss is amazing. I ve recommended so many people to him. He listens and cares about his patients.


May 18, 2021

I had been terrified to get on medication but Dr. Weiss is awesome and listened to my concerns, and he is not pushy. He also lets me know how my medication will interact with other meds.


April 30, 2021

Dr. Weiss is easy to talk with about my problems and issues. He s done a great job with my medication management.


April 27, 2021

Dr. Weiss is amazing. Couldn t be happier with the care from him.


April 27, 2021

Very high-quality care provided by Dr. Weiss. He is responsive to needs and has made a huge positive impact on my quality of life and career. Couldn t be happier with Dr. Weiss and the entire team at Mindpath.


April 9, 2021

I enjoy the ease of the telehealth appointments.


April 6, 2021

I can talk to him easily, he listens well, he has found the right medications for me.


April 5, 2021

Dr. Weiss has really helped me better manage my treatment-resistant depression. He is thorough, compassionate & seems invested in improving my overall mental health.


April 5, 2021

I appreciate the ease of working with my therapist.


April 1, 2021

Dr. Weiss is really wonderful. Very compassionate and really takes the time to listen and discuss.


May 26, 2020

It is definitely something I would do again. The provider was caring, explained the treatment plan

Tropical Storm Isaias is headed towards the Carolinas

Tropical Storm Isaias is headed towards the Carolinas. Please note that we plan to be open for appointments; however, be aware that power outages may be widespread which may impact telehealth and other appointments. We may not know until the last minute in all of our locations on Tuesday. Please be patient. We will waive missed appointment charges on Tuesday, August 4th in light of complications from the weather. If you and your provider are unable to connect, we will reach out to reschedule your appointment as soon as possible.