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MindPath Care Centers at Carolina Partners in Mental HealthCare, PLLC

Spravato (esketamine)

**Please Note: MindPath is currently not accepting new patients for Spravato treatment.
See if you may be a candidate for TMS.**

Introducing Spravato (esketamine) treatment at MindPath

If you or your loved one has depression, you know that finding the right treatment can be difficult. You may have tried several types of antidepressants, only to be left feeling frustrated and discouraged.

You are not alone. In fact, of the more than 16 million U.S. adults with depression, about one-third of them do not find relief with standard treatment.

Now, MindPath is excited to offer Spravato (esketamine) for patients who have struggled to find an effective treatment for their depression.

How does Spravato work?

Spravato is the first nasal spray approved by the FDA to treat depression in adults who have not found relief with other antidepressants. It helps treat depression symptoms by targeting different neural receptors in the brain.

Spravato can help patients in many ways:

  • Stabilizing mood
  • Decreasing the severity of depression
  • Delaying the return of symptoms
  • Taking effect in days rather than weeks

In one study of Spravato, patients who stayed on Spravato after 16 weeks of therapy had better results than patients who stopped therapy. Patients who received Spravato also showed a greater reduction of depression symptoms than patients who received only a traditional oral antidepressant.

“I’ve struggled with depression for most of my life,” one patient said in a testimonial. “I couldn’t physically do anything and had to drop out of college. I tried a long list of antidepressants but none of them worked for me. Spravato has made a big difference in my depression symptoms. I’m back in college full time now and growing as a person.”

How is Spravato taken?

The FDA approved the use of Spravato with another oral antidepressant, to target different neural receptors in the brain.

Currently, Spravato nasal spray is only available under provider supervision at a certified doctor’s office or clinic. Most people receiving Spravato should start with a 56 mg dose per visit. Patients may start with two treatments per week for 4 weeks, with treatments then tapered down for maintenance.

Each time you receive Spravato through a nasal spray device, your provider will observe you and check up on you to determine when you’re ready to leave. This will take about 2 hours each treatment session.

What are the side effects of Spravato?

Since esketamine is used in anesthesia, it has many of the same potential side effects as other anesthetics and pain medications. Because of these possible side effects, your healthcare provider will observe you for about 2 hours after you receive your dose of Spravato.

Potential side effects of Spravato include:

  • Sedation
  • Dissociation
  • Increased blood pressure
  • Nausea, vomiting
  • Dizziness or vertigo
  • Anxiety
  • Decreased feeling or sensitivity (hypoesthesia)
  • Increased blood pressure
  • Feeling drunk
  • Impaired ability to drive or operate other machinery

Is Spravato right for me?

You may be a good candidate for Spravato if you:

  • Have treatment-resistant depression
  • At least two other antidepressants have not helped
  • Do not qualify for transcranial magnetic stimulation (TMS) therapy
  • Are not pregnant
  • Do not have hypersensitivity to ketamine
  • Do not have a history of the following:
    • Uncontrolled hypertension
    • Cardiovascular disease
    • Stroke
    • Aneurysms
    • Hallucinations, delusions, or suicidal behavior
    • Drug abuse or dependence

“Esketamine is the first new medication for depression in many years with a totally different mechanism of action,” says Dr. Sandeep Vaishnavi, at MindPath Care Centers at Situs Court, Raleigh. “It can act quickly, potentially in days rather than weeks or months, and it may work for patients when previous medications have not.”

How can I get started with Spravato?

Spravato will soon be offered alongside traditional therapy at MindPath’s Raleigh and Durham locations. Call us at 919-929-9610 or visit our website to set up an appointment!

Although Spravato is not currently listed on carrier formularies, some patients have received approval for Spravato from their insurers. Contact your insurance carrier to find out if you can be approved for coverage of Spravato. Janssen Pharmaceuticals also offers copay assistance for qualifying patients.

There is hope for depression.

At MindPath Care Centers, we believe that each person has a right to compassionate, thorough, personalized care. Since 1994, we have made your empowerment our priority, and are committed to providing the resources and knowledge you need to thrive.

Providing individual, patient-centered care not only benefits the individual, but strengthens our families and communities. We are committed to being an accessible, comfortable, safe place to receive mental health care from over 150 experienced, professional associates. This diverse network allows our experts to collaborate to provide the best care possible.

If you have struggled with depression and felt frustrated by ineffective treatments, there is still hope and help for you. Call now to be matched with a specialist near you. Take your first step to living to your full potential!

Healthcare Begins with Mindcare™

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