SPRAVATO®: Depression Treatment for Antidepressant Resistance

What is SPRAVATO®?

It is incredibly demoralizing to have a mood disorder that resists treatment again and again. It can feel like your last hope has failed you. But one of the great things about mental health care is that they are constantly working on new ways of treating people–and we’d like to introduce you to a wonderful alternative treatment.

SPRAVATO®, also known as esketamine, is a nasal spray that is self-administered by the patient while being monitored by a specially trained medical assistant at regular intervals. It is taken alongside other antidepressants and therapy, targeting different neural receptors in the brain. Is has been shown to aid in decreasing depression and restoring stability to patients’ moods.

How does SPRAVATO® work?

“Esketamine is the first new medication for depression in many years with a totally different mechanism of action,” says Dr. Vaishnavi, MindPath’s neuropsychiatric expert. “It can act quickly, potentially in days rather than weeks or months, and it may work for patients when previous medications have not.”

Various trials have shown SPRAVATO® to be quite effective. After 16 weeks of therapy, those patients who stayed on SPRAVATO® did better than those who stopped therapy and showed a greater reduction of depression symptoms than those who received only an oral antidepressant.

SPRAVATO® is only available at certified SPRAVATO® treatment centers under the supervision of a healthcare provider.

For more information, including potential side effects and other risks and benefits, please visit the SPRAVATO® website >

How can I get started with SPRAVATO®?

To see if SPRAVATO® is right for you, please complete the form below to request your free assessment. If you have questions or concerns, please contact us at 877-876-3783 and our intake team will be happy to help.

Many major commercial and Medicare plans now cover SPRAVATO® treatment for depression. MindPath Care Centers now accepts Medicare, BCBS, Cigna, Aetna, and Tricare for SPRAVATO® treatment. As with other medical treatments, contact your specific insurance provider to confirm whether SPRAVATO® is covered for you.

Request a Free Online Assessment

SPRAVATO® Certified Clinicians

Director – Sandeep Vaishnavi, MD, PhD

MD in Psychiatry from the University of Alabama
Residency in Psychiatry at Duke University
Residency in Clinical Psychopharmacology at Duke University and GlaxoSmithKline
Fellowship in Behavioral Neurology and Neuropsychiatry at Johns Hopkins University School of Medicine
Double board-certified – Behavioral Neurology & Neuropsychiatry and General Psychiatry

E. Elise Herman

Psychiatrist
E. Elise Herman

MD

Psychiatrist

Charlotte, NC
E. Elise Herman

MD

View Full Bio
I offer medication management

Transcranial Magnetic Stimulation (TMS)
ADD/ADHD
Adjustment Concerns
Alcohol Use
Anxiety / Stress
Bipolar I & II
Depression
LGBTQ+ Care
OCD
Post-Partum / Pregnancy Depression
PTSD/Trauma

Telehealth
TMS

In-network with:

Aetna NC
BCBS NC
Cigna NC
Tricare NC
Magellan NC
Medcost NC
Medicare NC
UBH NC

View Full Bio
Jenny Smith

Psychiatrist
Jenny Smith

MD

Psychiatrist

Raleigh, NC | Telehealth
Jenny Smith

MD

View Full Bio
I offer medication management and telehealth

ADD/ADHD
Adjustment Concerns
Alcohol Use
Anxiety / Stress
Bipolar I & II
Depression
Eating Disorder
OCD
Post-Partum / Pregnancy Depression
PTSD/Trauma

In-network with:

Aetna NC
BCBS NC
Tricare NC
Medicare NC
UBH NC
Humana NC
Worker’s Comp
Gateway NC
Alignment NC

View Full Bio
Caleb Alan Whitenack

Psychiatrist
Caleb Alan Whitenack

MD

Psychiatrist

Durham, NC | Telehealth
Caleb Alan Whitenack

MD

View Full Bio
I offer medication management and telehealth

Transcranial Magnetic Stimulation (TMS)
ADD/ADHD
Adjustment Concerns
Anxiety / Stress
Bipolar I & II
Depression
OCD
Post-Partum / Pregnancy Depression
PTSD/Trauma

Telehealth
TMS

In-network with:

Aetna NC
BCBS NC
Cigna NC
Magellan NC
Medcost NC
UBH NC
Humana NC
Alignment NC

View Full Bio

What our Patients Say

I have struggled for decades to get [my depression] under control. I've taken every SSRI, SNRI, and tricyclic on the market, practically. Psychologist visits, you name it. Nothing has worked like the Spravato treatments I get. My depression has decreased by 50% and I'm continuing to get better. I am an RN and observant to my caregivers. The team I have here has been amazing. Check it out. Aren't you tired of suffering?

I’ve struggled with depression for most of my life. I would spend 18 to 20 hours a day sleeping. I couldn’t physically do anything and had to drop out of college. I tried a long list of antidepressants but none of them worked for me. Spravato has made a big difference in my depression symptoms. I’m back in college full time now and growing as a person.

Results may vary according to individual.